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Systemic Lupus Erythematosus (SLE) is an autoimmune disease in which the immune system attacks its own tissues and organs [1][ 9]. It is the most common type of lupus [1] and can affect many parts of the body [3]. Symptoms may include fatigue, joint pain, skin rashes, fever, and organ damage [2][ 6]. The cause of SLE is unknown but it has been linked to genetic factors as well as environmental triggers such as infections or medications [4]. Treatment typically involves lifestyle changes such as avoiding sun exposure and stress management along with medications to reduce inflammation or suppress the immune system [5][6][7][8].


[1]: Systemic Lupus Erythematosus (SLE) | CDC (https://www.cdc.gov/lupus/facts/detailed.html)
[2]: Systemic lupus erythematosus: MedlinePlus Medical Encyclopedia (https://medlineplus.gov/ency/article/000435.htm)
[3]: Systemic Lupus Erythematosus (Lupus) - Who gets it? | NIAMS (https://www.niams.nih.gov/health-topics/lupus)
[4]: Systemic lupus erythematosus: MedlinePlus Genetics (https://medlineplus.gov/genetics/condition/systemic-lupus-erythematosus/)
[5]: Lupus (https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Lupus)
[6]: Systemic Lupus Erythematosus (SLE): Practice Essentials ... (https://emedicine.medscape.com/article/332244-overview)
[7]: Lupus - Symptoms and causes - Mayo Clinic (https://www.mayoclinic.org/diseases-conditions/lupus/symptoms-causes/syc-20365789)
[8]: Lupus: Symptoms, Causes, Types & Treatments (https://my.clevelandclinic.org/health/diseases/4875-lupus)

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Systemic lupus erythematosus (SLE) is an autoimmune disorder that affects multiple organs and systems in the body. It is a chronic, inflammatory disease that can cause inflammation of the skin, joints, kidneys, heart, lungs, brain and other organs. Symptoms vary from person to person but may include fatigue, joint pain or swelling, fever and rash. Treatment typically involves medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids and immunosuppressants.