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Sjögren's syndrome is a chronic (long-lasting) autoimmune disorder that happens when the immune system attacks the glands that make moisture [1][2][3]. The most common symptoms are dry eyes and a dry mouth [1], but it can also cause fatigue and other systemic symptoms such as joint pain, rashes, and difficulty breathing [2]. It is an autoimmune disease where the immune system mistakenly attacks healthy cells instead of invading bacteria [4][7]. Diagnosis typically involves blood tests to look for autoantibodies associated with Sjögren's syndrome as well as imaging tests to check for inflammation in affected areas [5]. Treatment usually includes medications to reduce inflammation or suppress the immune system along with lifestyle changes such as drinking more fluids and using artificial tears or saliva substitutes. In some cases surgery may be necessary to treat complications from Sjögren's syndrome[6][8]

[1]: Sjogren's syndrome - Symptoms and causes - Mayo Clinic (
[2]: Sjogren's Syndrome (
[3]: Sjogren's Syndrome Symptoms - Dry Mouth & Eyes | NIAMS (
[4]: Sjogren's Syndrome | Dry Mouth | Dry Eyes | MedlinePlus (
[5]: Sjögren's Syndrome: Causes, Symptoms, Diagnosis & Treatments (
[6]: Sjögren syndrome: MedlinePlus Genetics (
[7]: Sjogren's Syndrome: Symptoms, Causes, Diagnosis, Treatment (
[8]: Sjogren Syndrome - StatPearls - NCBI Bookshelf (


Sjögren syndrome is an autoimmune disorder that affects the body's ability to produce tears and saliva. It is characterized by dry eyes, dry mouth, fatigue, joint pain, and other symptoms. Treatment typically involves medications to reduce inflammation and relieve symptoms.