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Parkinson's disease is a progressive disorder that affects the nervous system and the parts of the body controlled by the nerves [1]. It is caused by a loss of nerve cells in an area of the brain called the substantia nigra [10], which leads to decreased production of dopamine, a chemical that coordinates movement [4][ 6]. Symptoms include unintended or uncontrollable movements such as shaking, stiffness, and difficulty with balance and coordination [1][2][3]. Treatment options vary depending on severity but may include medications, physical therapy, surgery or deep brain stimulation (DBS) [5][6][7][8]. The Michael J. Fox Foundation for Parkinson's Research is dedicated to finding a cure for Parkinson's disease through an aggressively funded research agenda and to ensuring those living with PD have access to treatments they need today[9].


[1]: Parkinson's disease - Symptoms and causes - Mayo Clinic (https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055)
[2]: Parkinson's Foundation: Homepage (https://www.parkinson.org/)
[3]: Parkinson's Disease: Causes, Symptoms, and Treatments | National ... (https://www.nia.nih.gov/health/parkinsons-disease)
[4]: Parkinson's disease - Wikipedia (https://en.wikipedia.org/wiki/Parkinson%27s_disease)
[5]: Parkinson's Disease: What It Is, Causes, Symptoms & Treatment (https://my.clevelandclinic.org/health/diseases/8525-parkinsons-disease-an-overview)
[6]: Parkinson's Disease | PD | MedlinePlus (https://medlineplus.gov/parkinsonsdisease.html)
[7]: Parkinson's 101 | Parkinson's Disease (https://www.michaeljfox.org/parkinsons-101)
[8]: Parkinson's Disease | Johns Hopkins Medicine (https://www.hopkinsmedicine.org/health/conditions-and-diseases/parkinsons-disease)
[9]: The Michael J. Fox Foundation for Parkinson's Research ... (https://www.michaeljfox.org/)
[10]: Parkinson's disease - Causes - NHS (https://www.nhs.uk/conditions/parkinsons-disease/causes/)

AI

Parkinson's disease is a progressive neurological disorder that affects movement. It is caused by the death of dopamine-producing cells in the brain, which leads to impaired motor control and other symptoms such as tremors, stiffness, slowness of movement, and difficulty with balance. There is no cure for Parkinson's disease but medications can help manage symptoms and slow progression of the condition. Other treatments include physical therapy, speech therapy, occupational therapy, and surgery.