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Nonalcoholic fatty liver disease (NAFLD) is an umbrella term for a range of liver conditions affecting people who drink little to no alcohol [1]. It is characterized by the accumulation of excess fat in the liver cells that is not caused by alcohol [4]. Symptoms may include fatigue, abdominal pain, and jaundice. The diagnosis of NAFLD can be confirmed with a biopsy or imaging tests such as ultrasound or MRI [2]. Treatment options include lifestyle changes such as diet and exercise, medications, and surgery depending on the severity of the condition [3]. There are two types of NAFLD: nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH). NASH involves inflammation and damage to the liver cells which can lead to cirrhosis if left untreated [5]. A scoring system called NAFLD activity score has been developed to help diagnose NASH based on histological abnormalities seen on a biopsy specimen[6].


[1]: Nonalcoholic fatty liver disease - Symptoms and causes - Mayo Clinic (https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567)
[2]: Nonalcoholic Fatty Liver Disease (NAFLD) & NASH | NIDDK (https://www.niddk.nih.gov/health-information/liver-disease/nafld-nash)
[3]: Nonalcoholic Fatty Liver Disease | Johns Hopkins Medicine (https://www.hopkinsmedicine.org/health/conditions-and-diseases/nonalcoholic-fatty-liver-disease)
[4]: Nonalcoholic Fatty Liver Disease (NAFLD) - American Liver ... (https://liverfoundation.org/liver-diseases/fatty-liver-disease/nonalcoholic-fatty-liver-disease-nafld/)
[5]: Fatty Liver Disease | MedlinePlus (https://medlineplus.gov/fattyliverdisease.html)
[6]: Nonalcoholic fatty liver disease (NAFLD) activity score and the ... (https://pubmed.ncbi.nlm.nih.gov/21319198/)

AI

fatty liver disease (NAFLD) is a condition in which fat builds up in the
liver. It is one of the most common causes of chronic liver disease, affecting an estimated 25-30% of people worldwide. NAFLD can range from mild to severe and may lead to serious complications such as cirrhosis or even liver failure if left untreated. The exact cause of NAFLD is unknown, but it is often associated with obesity, diabetes, high cholesterol levels, and metabolic syndrome. Treatment for NAFLD typically involves lifestyle changes such as weight loss through diet and exercise, controlling blood sugar levels if you have diabetes or prediabetes, avoiding alcohol consumption and taking medications that target specific symptoms or conditions related to your fatty liver disease.