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Gastroesophageal reflux disease (GERD) is a condition in which the stomach contents, including acid, reflux back up into the esophagus [3]. GERD can cause symptoms such as heartburn, regurgitation of stomach contents, and difficulty swallowing [7], and may lead to Barrett's esophagus [6]. Barrett's esophagus is a complication of GERD that occurs when cells in the lining of the lower part of the esophagus become abnormal due to long-term exposure to stomach acid. People with Barrett's esophagus may not experience any symptoms but are at an increased risk for developing cancerous changes in their cells [1][2][4][5]. Treatment options for GERD include lifestyle modifications such as avoiding certain foods or eating smaller meals more frequently, medications such as antacids or proton pump inhibitors (PPIs), and surgery if necessary [8][9].


[1]: Barrett's esophagus - Symptoms and causes - Mayo Clinic (https://www.mayoclinic.org/diseases-conditions/barretts-esophagus/symptoms-causes/syc-20352841)
[2]: Barrett's Esophagus: What is it, Symptoms, Treatment & Tests (https://my.clevelandclinic.org/health/diseases/14432-barretts-esophagus)
[3]: Barrett's Esophagus | Johns Hopkins Medicine (https://www.hopkinsmedicine.org/health/conditions-and-diseases/barretts-esophagus)
[4]: From reflux esophagitis to Barrett's esophagus and esophageal ... (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419061/)
[5]: GERD, Barrett's Esophagus and the Risk for Esophageal Cancer (https://www.asge.org/home/for-patients/patient-information/understanding-gerd-barrett-39-s)
[6]: The relationship between gastroesophageal reflux disease and its ... (https://pubmed.ncbi.nlm.nih.gov/8995932/)
[7]: Patient education: Barrett's esophagus (Beyond the Basics ... (https://www.uptodate.com/contents/barretts-esophagus-beyond-the-basics)
[8]: Patient education: Gastroesophageal reflux disease in adults ... (https://www.uptodate.com/contents/gastroesophageal-reflux-disease-in-adults-beyond-the-basics)
[9]: Barrett's Esophagus: Symptoms, Causes, and Treatments (https://www.webmd.com/heartburn-gerd/guide/barretts-esophagus-symptoms-causes-and-treatments)

AI

Gastroesophageal reflux disease (GERD) is a chronic digestive disorder that occurs when stomach acid or, occasionally, bile flows back into the esophagus. This backward flow of acid is called reflux and can cause heartburn and other symptoms. GERD can also lead to Barrett's esophagus, which is a condition in which the lining of the esophagus changes due to long-term exposure to stomach acid. People with Barrett's esophagus are at an increased risk for developing cancer of the esophagus. Treatment options for GERD include lifestyle modifications such as avoiding certain foods and beverages that trigger symptoms, medications such as antacids or proton pump inhibitors (PPIs), and surgery if necessary.