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Barrett's esophagus is a precancerous condition that may lead to esophageal adenocarcinoma [1]. People with Barrett's esophagus have an increased risk of developing esophageal cancer, although the risk is small (0.4-0.5% per year) [2][ 9]. The diagnosis of Barrett's Esophagus increases the risk for developing high grade dysplasia and/or cancer by approximately 30 times compared to those without it [3]. In an endoscopic series of patients, 0.9%-4.5% had Barrett's Esophagus and the prevalence of cancer, high grade dysplasia, and low grade dysplasia in Barrett's was found to be 1%, 4%, and 11%, respectively [4].


[1]: Barrett's Esophagus: What is it, Symptoms, Treatment & Tests (https://my.clevelandclinic.org/health/diseases/14432-barretts-esophagus)
[2]: GERD, Barrett's Esophagus and the Risk for Esophageal Cancer (https://www.asge.org/home/for-patients/patient-information/understanding-gerd-barrett-39-s)
[3]: Barrett esophagus and risk of esophageal cancer: a clinical review (https://pubmed.ncbi.nlm.nih.gov/23942681/)
[4]: Facts | Thompson Cancer Survival Center (https://www.thompsoncancer.com/barretts/barretts-esophagus-facts/)

AI

Barrett's esophagus is a condition in which the tissue lining the esophagus changes to resemble the tissue that lines the intestine. This change increases a person’s risk of developing cancer of the esophagus, also known as esophageal adenocarcinoma. While this type of cancer is rare, it can be very aggressive and difficult to treat. Treatment typically involves surgery or chemotherapy and radiation therapy.