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Atherosclerosis is a common condition that develops when a sticky substance called plaque builds up inside your arteries [1]. Plaque (fatty deposits) build up in your arteries is called atherosclerosis [2]. These deposits are made up of cholesterol, fatty substances, calcium and other cellular waste products [3]. Atherosclerosis is a type of thickening or hardening of the arteries caused by a buildup of plaque in the inner lining of an artery [4]. It can increase your risk for heart attack, stroke and other serious conditions. Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called lesions [5]. Symptoms may include chest pain, shortness of breath and leg pain. Treatment includes lifestyle changes such as diet modification and exercise as well as medications to lower cholesterol levels. Other treatments may include angioplasty or bypass surgery if needed [6][7][8]. Atherosclerosis covers basic and translational research approaches to arterial and vascular biology and disease, as well as their risk factors[9]

[1]: Atherosclerosis - What Is Atherosclerosis? | NHLBI, NIH (
[2]: What is Atherosclerosis? | American Heart Association (
[3]: Atherosclerosis: Symptoms, Causes, Diagnosis, and Treatment (
[4]: Atherosclerosis | Johns Hopkins Medicine (
[5]: Atherosclerosis - Wikipedia (
[6]: Atherosclerosis: Causes, Symptoms, Risks & Tests (
[7]: Atherosclerosis | Arteriosclerosis | MedlinePlus (
[8]: Atherosclerosis: Symptoms, Causes, Diagnosis, and Treatment (
[9]: Atherosclerosis: Home Page (


Atherosclerosis is a condition in which plaque builds up inside the arteries. Plaque is made up of fat, cholesterol, calcium and other substances found in the blood. Over time, this buildup can narrow or block the arteries and reduce blood flow to organs and tissues. This can lead to serious health problems such as heart attack, stroke, aneurysm or kidney failure. Atherosclerosis is often caused by lifestyle factors such as smoking, high cholesterol levels, diabetes and obesity. Treatment may include lifestyle changes (such as quitting smoking), medications (such as statins) or surgery (such as angioplasty).